Pesquisa | SciELO

The aim of this work was to identify and quantify the metabolites present in the roots of Combretum lanceolatum inoculated with its endophytic fungi. The metabolomics was accomplished using the 1H nuclear magnetic resonance (NMR) spectral data and evaluated via rNMR software and Madison Metabolomics Consortium Database (MMCD). The principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA) showed that plants inoculated with Trichoderma spirale (Ts) present differentiation and discrimination over the time compared to control. Seven days after Ts fungal inoculation, 15 metabolites were identified at different concentrations comparing to the control plants. The plants inoculated with Ts fungus present the metabolites spermidine and pantothenate in higher concentrations and 3-hydroxybutyric acid and b-alanine in lower concentrations compared to control plants, indicating any response to biotic stress. These metabolites are involved in various plant processes, including secondary metabolites biosynthesis, energy metabolism and self-defense. Therefore, this work demonstrates the diversification of primary metabolites composition influenced by endophytes inoculation.

https://doi.org/10.21577/0103-5053.20220103

Biogenic production of selenocysteine by Enterococcus faecium ABMC-05: an indigenous lactic acid bacterium from fermented Mexican beverage
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ESCOBAR-RAMÍREZ, Meyli Claudia

; RODRÍGUEZ-SERRANO, Gabriela Mariana

; SALAZAR-PEREDA, Veronica

; CASTAÑEDA-OVANDO, Araceli

; PÉREZ-ESCALANTE, Emmanuel

; JAIMEZ-ORDAZ, Judith

; GONZÁLEZ-OLIVARES, Luis Guillermo

Food Science and Technology

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2023, Volume 43 elocation e63622

Resumo: En | Texto: En | PDF: En

Abstract Lactic acid bacteria have been studied for their ability to accumulate inorganic selenium, which is reduced to its elemental form or could be integrated into selenoproteins in the form of selenocysteine. This ability to produce bioavailable organic selenium for humans is an advantage that could be exploited in the production of functional foods. In this work, Enterococcus faecium ABMC-05 isolated from a traditional Mexican beverage (tepache) and with NCBI entry number OL413240 was used. Microorganism selenization was performed after the determination of minimal inhibitory concentration of Na2SeO3 (184 mg/L), which was calculated using the graphical method of Talmadge and Fitch. The selenium concentration of accumulated selenium was calculated by inductively coupled plasma optical emission spectroscopy (ICP-OES). The concentration of selenium at 48 h of fermentation was 39.92 mg/L, which represented 23.8% of selenium at medium. This value was consistent with those reported for other lactic acid bacteria. Finally, it was determined the selenocysteine presence in biomass recovery after fermentation using RP-HPLC technique. With these results it was confirmed the biogenic production of selenocysteine by Enterococcus faecium ABMC-05 using an inorganic source.

https://doi.org/10.1590/fst.63622

O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos
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Pereira, Rui Antunes

; Sousa, Marta

; Cidade, José Pedro

; Melo, Luís

; Lopes, Diogo

; Ventura, Sara

; Aragão, Irene

; Lima Neto, Raul Miguel de Freitas

; Molinos, Elena

; Marques, Ana

; Cardoso, Nelson

; Marino, Flávio

; Monteiro, Filipa Brás

; Oliveira, Ana Pinho

; Silva, Rogério C

; Real, André Miguel Neto

; Banheiro, Bruno Sarmento

; Reis, Renato

; Adão-Serrano, Maria

; Cracium, Ana

; Valadas, Ana

; Ribeiro, João Miguel

; Póvoa, Pedro

; Tapadinhas, Camila

; Mendes, Vítor

; Coelho, Luís

; Maia, Raquel

; Freitas, Paulo Telles

; Ferreira, Isabel Amorim

; Ramires, Tiago

; Val-Flores, Luís Silva

; Cascão, Mariana

; Alves, Rita

; Rodeia, Simão C

; Barrigoto, Cleide

; Cardiga, Rosa

; Silva, Maria João Ferreira da

; Vale, Bruno

; Fonseca, Tatiana

; Rios, Ana Lúcia

; Camões, João

; Pérez, Danay

; Cabral, Susana

; Ribeiro, Maria Inês

; Mendes, João João

; Gouveia, João

; Fernandes, Susana Mendes

Revista Brasileira de Terapia Intensiva

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Dez 2022, Volume 34 Nº 4 Páginas 433 - 442

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To analyze and compare COVID-19 patient characteristics, clinical management and outcomes between the peak and plateau periods of the first pandemic wave in Portugal. Methods: This was a multicentric ambispective cohort study including consecutive severe COVID-19 patients between March and August 2020 from 16 Portuguese intensive care units. The peak and plateau periods, respectively, weeks 10 - 16 and 17 - 34, were defined. Results: Five hundred forty-one adult patients with a median age of 65 [57 - 74] years, mostly male (71.2%), were included. There were no significant differences in median age (p = 0.3), Simplified Acute Physiology Score II (40 versus 39; p = 0.8), partial arterial oxygen pressure/fraction of inspired oxygen ratio (139 versus 136; p = 0.6), antibiotic therapy (57% versus 64%; p = 0.2) at admission, or 28-day mortality (24.4% versus 22.8%; p = 0.7) between the peak and plateau periods. During the peak period, patients had fewer comorbidities (1 [0 - 3] versus 2 [0 - 5]; p = 0.002) and presented a higher use of vasopressors (47% versus 36%; p < 0.001) and invasive mechanical ventilation (58.1 versus 49.2%; p < 0.001) at admission, prone positioning (45% versus 36%; p = 0.04), and hydroxychloroquine (59% versus 10%; p < 0.001) and lopinavir/ritonavir (41% versus 10%; p < 0.001) prescriptions. However, a greater use of high-flow nasal cannulas (5% versus 16%, p < 0.001) on admission, remdesivir (0.3% versus 15%; p < 0.001) and corticosteroid (29% versus 52%, p < 0.001) therapy, and a shorter ICU length of stay (12 days versus 8, p < 0.001) were observed during the plateau. Conclusion: There were significant changes in patient comorbidities, intensive care unit therapies and length of stay between the peak and plateau periods of the first COVID-19 wave.

RESUMO Objetivo: Analisar e comparar as características de pacientes críticos com a COVID-19, a abordagem clínica e os resultados entre os períodos de pico e de platô na primeira onda pandêmica em Portugal. Métodos: Este foi um estudo de coorte multicêntrico ambispectivo, que incluiu pacientes consecutivos com a forma grave da COVID-19 entre março e agosto de 2020 de 16 unidades de terapia intensiva portuguesas. Definiram-se as semanas 10 - 16 e 17 - 34 como os períodos de pico e platô. Resultados: Incluíram-se 541 pacientes adultos com mediana de idade de 65 [57 - 74] anos, a maioria do sexo masculino (71,2%). Não houve diferenças significativas na mediana de idade (p = 0,3), no Simplified Acute Physiology Score II (40 versus 39; p = 0,8), na pressão parcial de oxigênio/fração inspirada de oxigênio (139 versus 136; p = 0,6), na terapia com antibióticos na admissão (57% versus 64%; p = 0,2) ou na mortalidade aos 28 dias (24,4% versus 22,8%; p = 0,7) entre o período de pico e platô. Durante o período de pico, os pacientes tiveram menos comorbidades (1 [0 - 3] versus 2 [0 - 5]; p = 0,002); fizeram mais uso de vasopressores (47% versus 36%; p < 0,001) e ventilação mecânica invasiva na admissão (58,1% versus 49,2%; p < 0,001), e tiveram mais prescrição de hidroxicloroquina (59% versus 10%; p < 0,001), lopinavir/ritonavir (41% versus 10%; p < 0,001) e posição prona (45% versus 36%; p = 0,04). Entretanto, durante o platô, observou-se maior uso de cânulas nasais de alto fluxo (5% versus 16%; p < 0,001) na admissão, remdesivir (0,3% versus 15%; p < 0,001) e corticosteroides (29% versus 52%; p < 0,001), além de menor tempo de internação na unidade de terapia intensiva (12 versus 8 dias; p < 0,001). Conclusão: Houve mudanças significativas nas comorbidades dos pacientes, nos tratamentos da unidade de terapia intensiva e no tempo de internação entre os períodos de pico e platô na primeira onda da COVID-19.

https://doi.org/10.5935/0103-507x.20210037-pt

CONSUMO DE OVOS E DOENÇAS VASCULARES - QUAL A SUA ASSOCIAÇÃO?
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d`Agua, Mafalda Rodrigues Guapo Borda

; Sá, Mariana de Oliveira

; Serrano, Mariana Seoane

; Lage, Vera Mónica Carneiro

Acta Portuguesa de Nutrição

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Set 2022, Nº 30 Páginas 40 - 45

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT INTRODUCTION: Although eggs are rich in nutrients, they are the main source of cholesterol in our diet. The association between regular egg consumption and cardiovascular disease is uncertain. This Evidence-Based Review aims to clarify the effect of egg consumption on cardiovascular disease in adults without previous cardio and cerebrovascular events. METHODOLOGY: Bibliographic research using the MeSH terms “Eggs” and “Cardiovascular Diseases”. Studies published in the last 5 years were included according to the criteria: (P) Adults with no established history of cardiovascular disease; (I) Egg consumption; (C) Absence/lower egg consumption (O) Cardiovascular Events. To assess the levels of evidence and attribution of strengths of recommendation, the SORT scale of the American Family Physician was applied. After reading the abstracts and simultaneous application of the inclusion and exclusion criteria, only 3 articles met our criteria: 1 meta-analysis and 2 systematic reviews with meta-analysis (level of evidence 2). RESULTS: This MA demonstrated that the intake of up to 6 eggs/week is inversely associated with cardiovascular events and that consumption of up to 1 egg/day was associated with a decreased of cardiovascular disease incidence. In addition, no association was made with stroke risk. One of the systematic reviews/meta-analysis demonstrated that higher egg consumption (> 1 egg/ day) was not associated with an increased risk of cardiovascular disease or stroke, but rather with a reduced risk of coronary heart disease. In turn, the other systematic reviews/meta-analysis also showed that moderate egg consumption is not associated with an increased risk of cardiovascular disease. CONCLUSIONS: Current evidence is not sufficient to consider egg consumption unhealthy, nor to generalize potential harmful effects in individuals without previous cardiovascular events. Therefore, while awaiting for better studies, there is no need to discourage egg consumption at this population’s level.

RESUMO INTRODUÇÃO: Apesar dos ovos serem ricos em nutrientes são a principal fonte de colesterol na dieta. A associação entre o consumo regular de ovos e o risco de doença cardiovascular é incerta. Assim, esta Revisão Baseada na Evidência tem como objetivo clarificar o efeito do consumo de ovos nas doença cardiovascular em adultos sem eventos cardio e cerebrovasculares prévios. METODOLOGIA: Pesquisa bibliográfica aplicando os termos MeSH “Eggs" and "Cardiovascular Diseases". Incluídos estudos publicados nos últimos 5 anos segundo os critérios: (P) Adultos sem história de doença cardiovascular estabelecida; (I) Consumo de ovos; (C) Ausência/menor consumo de ovos; (O) Eventos Cardiovasculares. Para avaliação dos níveis de evidência e atribuição de forças de recomendação recorreu-se à escala SORT da American Family Physician. Após leitura dos resumos e aplicação simultânea dos critérios de inclusão e exclusão selecionaram-se apenas 3 artigos: 1 meta-análise e 2 revisões sistemáticas com meta análise (nível de evidência 2). RESULTADOS: A meta-análise demonstrou que a ingestão de até 6 ovos/semana está inversamente associada a eventos Cardiovasculares e que o consumo de até 1 ovo/dia foi associado a uma diminuição da incidência de doença cardiovascular. Além disso, nenhuma associação foi relacionada com o risco de acidente vascular cerebral. Uma das revisões sistemáticas /meta-análise demonstrou que um maior consumo de ovos (> 1 ovo/dia) não foi associado ao aumento do risco de doença cardiovascular nem de acidente vascular cerebral, mas sim, à redução do risco de doença coronária. Por sua vez, a outra revisão sistemática /meta- análise também mostrou que o consumo moderado de ovos não está associado a um aumento do risco de doença cardiovascular. CONCLUSÕES: As evidências atuais não são suficientes para considerar o consumo de ovos prejudicial à saúde, nem para generalizar potenciais efeitos prejudiciais em indivíduos sem eventos Cardiovasculares prévios. Portanto, enquanto se aguarda por um melhor design dos estudos, não há necessidade de desencorajar o consumo de ovos ao nível desta população.

https://doi.org/10.21011/apn.2022.3007

Prevenção do Tromboembolismo Venoso na Gravidez, Parto e Pós-Parto: Norma de Orientação Clínica
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Lima, Jorge

; Domingues, Ana Patrícia

; Amaral, Ana Cristina

; Borges, Augusta

; Nogueira-Silva, Cristina

; Serrano, Fátima

; Marques, Inês

; Pinto, Luísa

; Guimarães, Mariana

Acta Obstétrica e Ginecológica Portuguesa

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Mar 2022, Volume 16 Nº 1 Páginas 75 - 81

Resumo: Pt | Texto: Pt | PDF: Pt

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Guía de Práctica Clínica para el Manejo del Dolor en pacientes Oncológicos de una Red de Clínicas Privadas, Lima Perú
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Berenguel, Maria

; Buendia, Daniel

; Tejada, Paolet

; Manrique, Marco

; Perez, Laura

; Gil-Olivares, Fradis

; Serrano, Mariana

; Aliaga, Karina

Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo

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Jan 2022, Volume 15 Nº 1 Páginas 118 - 125

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN El presente artículo resume el proceso de elaboración de la Guía de Práctica Clínica (GPC) para el manejo de dolor en pacientes oncológicos. Este proceso se llevó a cabo con la participación de un equipo multidisciplinario de médicos asistenciales, metodólogos y diversos revisores externos (especialistas con dominio en la metodología y el tema). La priorización de preguntas PICO fue realizada por el Grupo Elaborador de la GPC (GEG), acordando trabajar cinco preguntas PICO. Para dar respuesta a las preguntas se realizó una búsqueda sistemática de GPC, revisiones sistemáticas y estudios primarios. Se utilizó la metodología GRADE y los lineamientos de la normativa nacional para la formulación de recomendaciones. Se formularon 12 recomendaciones (10 fuertes y 2 débiles), 5 puntos de buena práctica clínica y 4 cuadros consensuados sobre el manejo de dolor oncológico. Los temas que abarcaron las recomendaciones para el manejo de dolor en pacientes oncológicos fueron: intervención temprana de tratamiento, terapia analgésica en dolor leve a moderado y en dolor moderado a severo, dolor neuropático e intervenciones no farmacológicas.

ABSTRACT The article summarizes the process of elaboration of the Clinical Practice Guide (CPG) for the management of cancer patients. The elaboration process was carried out with the participation of a multidisciplinary team of assisting physicians, methodologists and various external reviewers (specialists with mastery in the methodology and the subject). The prioritization of PICO questions was carried out by the GPC Elaboration Group (GEG), after which 05 PICO questions were concluded. To answer the questions, a systematic search of CPGs, systematic reviews and primary studies was carried out. The “GRADE” methodology and the guidelines of national regulations were used to formulate recommendations. Twelve recommendations were made (ten strong and two weak), 5 points of good clinical practice, 04 consensus tables on the management of cancer pain. The topics that covered the recommendations for pain management in cancer patients were: early treatment intervention, analgesic therapy in mild to moderate pain and moderate to severe pain, neuropathic pain and non-pharmacological interventions.

https://doi.org/10.35434/rcmhnaaa.2022.151.1184

Agave juice improves survival and proteolytic activity of Lactobacillus rhamnosus GG during ripening of semi-ripened mexican cheese
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RAMÍREZ-GODÍNEZ, Juan

; GUTIÉRREZ-RODRÍGUEZ, Juan Francisco

; CONTRERAS-LÓPEZ, Elizabeth

; RODRÍGUEZ-SERRANO, Gabriela Mariana

; CASTAÑEDA-OVANDO, Araceli

; JAIMEZ-ORDAZ, Judith

; GONZÁLEZ-OLIVARES, Luis Guillermo

Food Science and Technology

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2022, Volume 42 elocation e30820

Resumo: En | Texto: En | PDF: En

Abstract The importance of functional foods added with probiotics and prebiotics is directly related with the promotion of the health benefits of human. In this study the survival of the probiotic Lactobacillus rhamnosus GG in a semi-ripened cheese added with agave juice, was determined. Cheese ripening was carried out at 14 °C for 35 days. The pH changes were measured and the hydrolysis of the protein was evaluated through the analysis of free amino groups by the trinitrobenzenesulfonic acid (TNBS) method and SDS-PAGE polyacrylamide gel electrophoresis. At the end of the study, in the symbiotic cheese, the viability of the probotic was increased in two logarithmic cycles (from 6.73 to 8.72 log CFU). A more active proteolytic process was observed with the addition of agave juice, due to the high production of low molecular weight peptides and the concentration of free amino groups (8.63 mg/L). The pH did not have a significant difference between the control and the cheese studied. With the obtained results, it is seen that agave juice is an ingredient that can be added to semi ripening cheeses with the objective of improving the survival capacity of probiotic microorganisms, which are used as starters.

https://doi.org/10.1590/fst.30820

Laboratory variables as predictors of progression in gastroenteropancreatic neuroendocrine tumors in different lines of antineoplastic treatments
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Armentano, Daniela Pezzutti Domigues

; Monteiro, Mariana Ribeiro

; Aguiar Jr., Pedro Nazareth

; Tsukamoto, Jessica Sayuri

; Pio, Raquel Baptista

; Arakelian, Renata

; Araujo, Raphael Leonardo Cunha

; Usón Junior, Pedro Luiz Serrano

einstein (São Paulo)

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2022, Volume 20 elocation eAO6985

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: To determine the association of red cell blood counts, and liver panel tests to predict outcomes in patients with gastroenteropancreatic neuroendocrine tumors who underwent systemic antineoplastic treatments. Methods: Patients with gastroenteropancreatic neuroendocrine tumors in systemic treatment were assessed according to laboratory tests within the same period. Progression free survival was determined by the period between the beginning of treatment and the date of progression. We used conditional models (PWP model) to verify the association between laboratory tests and tumor progression. The level of significance used was 5%. Results: A total of 30 treatments given to 17 patients in the intention-to-treat population were evaluated. Treatment included octreotide, lanreotide, everolimus, lutetium, and chemotherapy. We had statistically significant results in chromogranin A, neutrophils and platelets-to-lymphocyte ratio. The risk of progression increases by 2% with the addition of 100ng/mL of chromogranin A (p=0.034), 4% with the increase of 100 neutrophil units (p=0.006), and 21% with the addition of 10 units in platelets-to-lymphocyte ratio (p=0.002). Conclusion: Chromogranin A, neutrophils and platelets-to-lymphocyte ratio were associated with disease progression during systemic treatment in gastroenteropancreatic neuroendocrine tumors. Further prospective studies with larger cohorts are necessary to validate our findings.

https://doi.org/10.31744/einstein_journal/2022ao6985

Desprendimiento de retina regmatógeno pediátrico: una revisión
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Carranza-Casas, Mario

; López-Martínez, Mariana

; Ariza-Camacho, Enrique

; Matsui-Serrano, Rodrigo

; Aceves, Jorge E.

; Graue-Wiechers, Federico

Revista mexicana de oftalmología

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Dez 2021, Volume 95 Nº 6 Páginas 267 - 277

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Rhegmatogenous retinal detachment in children and adolescents is a challenging but relatively rare disorder that differs from its adult counterpart in terms of anatomical features, etiology, management, and prognosis. In this article, the clinical and etiopathogenic characteristics are highlighted, and an update is made on its surgical management. The aim is to provide a knowledge base on the benefits, risks and prognosis of rhegmatogenous retinal detachment surgery in children.

Resumen El desprendimiento de retina regmatógeno en niños y adolescentes es una situación desafiante, pero relativamente rara, que difiere de su contraparte en los adultos en cuanto a características anatómicas, etiología, manejo y pronóstico. En este artículo se destacan las características clínicas y etiopatogénicas, y se realiza una actualización sobre su manejo quirúrgico. El propósito es revisar en detalle dichas características, los factores de riesgo y la técnica de reparación inicial. Se busca proporcionar una base de conocimiento sobre los beneficios, los riesgos y el pronóstico de la cirugía de desprendimiento de retina regmatógeno en niños.

https://doi.org/10.24875/rmo.m21000181 132 downloads

10.

Clinical Characteristics and Mid-Term follow-up of Elderly Patients with Severe Aortic Stenosis not Eligible for TAVI
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Rezende, Mariana Oliveira

; Santos, Natasha Soares Simões dos

; Andrade, Alexandre Aguiar

; Francischini, Mônica Serrano

; Targino, Decarthon Vitor Dantas

; Souza, Caio Simoes

; Maldi, Carolina de Paulo

; Siqueira, Dimytri Alexandre Alvim de

; Bihan, David Costa de Souza Le

; Pinto, Ibraim

; Ramos, Auristela Isabel de Oliveira

International Journal of Cardiovascular Sciences

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Nov 2021, Volume 34 Nº 5 Páginas 34 - 40

Resumo: En | Texto: En | PDF: En

Abstract Background: The treatment for symptomatic severe aortic stenosis (AS) is the correction of valve stenosis by surgical valve replacement and more recently by transcatheter aortic valve implant (TAVI). However, in some high risk surgical patients, TAVI is not possible for technical or clinical reasons or due to the unavailability of the endoprosthesis. Objective: The aim of this study was to evaluate a mid-term follow-up of symptomatic severe AS patients who are not eligible for TAVI trials, as well as to identify the clinical features of these patients. Methods: This was an observational, retrospective study conducted with 475 symptomatic severe AS patients, evaluated by the Heart Team between 2000 and 2017. Inclusion criterias were: patients considered not to be eligible for TAVI. The Shapiro-Wilk test was applied to evaluate normality. Non-paired t and Mann-Whitney tests were applied for continuous variables, while the chi-squared and Fischer exact tests were applied for categorical variables, with a level of significance of p<0,05. Results: The heart team evaluated 475 patients: 25 (5.26%) died before any intervention could be proposed; 326 (68.3%) were submitted to TAVI, so the study population consisted of 124 patients not eligible for TAVI. Of these, 31 (25%) underwent surgery and 93 (75%) remained in clinical treatment. In a mean 56 months- follow-up the mortality in clinical group was 46.2%. In the surgical group the mortality was 23.9% (in-hospital 12.9% and late mortality 11% in a mean 47.4 months follow-up). The patients that died presented a significantly lower left ventricle ejection fraction (LVEF), a smaller valve area, and a larger end-systolic diameter of the LV. Conclusion: The mortality of the clinical group's patients was significantly higher than the surgical mortality (46.2% vs. 12.9%; p=0.021). The patients of the clinical group were older, weighed less, and had a higher incidence of renal failure and a higher STS score.

https://doi.org/10.36660/ijcs.20200177 87 downloads

11.

Variaciones Anatómicas de la Arteria Hepática: Patrones Vasculares Observados en 140 Hígados de Donante Cadavérico
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Cifone, Tomás

; Lassalle, Santiago Lihué

; Serrano-Bernárdez, Victoria Cristina

; Roggero, Agostina

; Benitez, Nicolás

; Garay, Verónica

; Bendersky, Mariana

International Journal of Morphology

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Out 2021, Volume 39 Nº 5 Páginas 1391 - 1394

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

SUMMARY: The purpose of this article is to analyze the hepatic artery variations observed from the use of cadaveric donor livers for orthotopic transplantation among our population. A retrospective study of a liver transplant cohort including 140 donor livers was conducted between June 2011 and January 2021. The vascular arterial anatomy of the transplanted livers was classified according to Hiatt’s classification system. Classic hepatic artery variant: Type I: 62 cases (65.7 %). Non-classic hepatic artery variants: 48 cases (34.3 %), corresponding to: Type II: 12 cases (8.6 %), Type III: 18 cases (12.9 %), Type IV: 7 cases (5 %), Type V: 10 cases (7.1 %). No case of Type VI variant was identified. One case (0.7 %) not included in Hiatt’s classification was found, corresponding to an accessory left hepatic artery originating from the aorta. Precise knowledge regarding the most prevalent variations, as well as those that are the least common, is fundamental to upper abdominal surgical procedures.

RESUMEN: El objetivo de este trabajo es analizar las variantes de la arteria hepática observadas en hígados de donantes cadavéricos empleados para trasplante ortotópico de hígado en nuestra población. Se efectuó un estudio retrospectivo de una cohorte de 140 trasplantes entre junio del año 2011 y enero del año 2021. La anatomía vascular arterial de los injertos hepáticos fue clasificada de acuerdo a la descripción de Hiatt. Variante clásica de la arteria hepática - Tipo I: 62 casos (65,7 %). Variante no clásica de la arteria hepática: 48 casos (34,3 %), correspondientes a: Tipo II: 12 casos (8,6 %), Tipo III: 18 casos (12,9 %), Tipo IV: 7 casos (5 %), Tipo V: 10 casos (7,1 %). No se encontró ningún caso de variante Tipo VI. Se halló 1 caso (0,7 %) no descrito en esta clasificación correspondiente a una arteria hepática izquierda accesoria que se originaba de la aorta. El conocimiento preciso de las variaciones más prevalentes, y también de las menos frecuentes, es fundamental para los procedimientos quirúrgicos que se realizan en el abdomen superior.

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12.

Representação social da enfermagem de reabilitação: pensamento social dos enfermeiros
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Oliveira, Isabel

; Ferreira, Elisabete

; Neves, Daniela

; Carvalho, Ana Margarida

; Sílvia, Mariana

; Serrano, Liliana

; Delgado, Bruno

Revista de Investigação & Inovação em Saúde

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Jun 2021, Volume 4 Nº 1 Páginas 35 - 46

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Marco contextual: la calidad de la salud es una tarea multiprofesional, en la que la enfermería rehabilitadora aporta valor, por lo que entender su representación social puede aportar contribuciones relevantes para incrementar la visibilidad de la profesión promoviendo cambios. Objetivo: describir la representación social de la enfermería de rehabilitación para enfermeras. Metodología: Estudio cualitativo, exploratorio y descriptivo, en una accidental muestra probabilística con 110 participantes. La recolección de datos se realizó a través de una prueba de libre asociación de palabras, a través de medios electrónicos, a los enfermeros de la red de contactos de una institución de educación superior. En el tratamiento de los datos utilizamos el software informático IRAMUTEQ. Resultados: El núcleo central las expresiones autonomía, recuperación y kinesiterapia, reforzadas por la primera periferia: independencia, entrenamiento de la marcha y cuidado. Los dominios emergentes o las competencias comunes, como el ejercicio físico y la gestión, eran menos relevantes para la estructura de la representación social. Conclusión: Si no es posible construir un pensamiento social dentro de la profesión que traduzca el mandato social de la enfermería de rehabilitación, es posible que la población tampoco lo alcance, lo que podría tener implicaciones para la demanda de cuidados.

Resumo Enquadramento: a qualidade em saúde é uma tarefa multiprofissional, na qual a enfermagem de reabilitação acrescenta valor pelo que, a compreensão a sua a representação social, poderá proporcionar contributos relevantes para aumentar a visibilidade da profissão e promover mudanças nas práticas e nos contextos de prática clínica. Objetivo: descrever a representação social da enfermagem de reabilitação para os enfermeiros. Metodologia: estudo qualitativo, exploratório e descritivo, numa amostra não probabilística acidental com 110 participantes, tendo como população alvo enfermeiros. A recolha de dados foi efetuada através de um teste de associação livre de palavras, por meio eletrónico, aos enfermeiros da rede de contatos de uma instituição de ensino superior. O tratamento de dados foi realizado através do software informático IRAMUTEQ. Resultados: o núcleo central da representação social evidenciou as expressões autonomia, recuperação e cinesiterapia, reforçado pela primeira periferia - independência, treino de marcha e cuidar. Domínios emergentes ou competências comuns, como o exercício físico e a gestão, foram menos relevantes para a estrutura da representação social. Conclusão: Não se conseguindo construir dentro da profissão um pensamento social que traduza o mandato social da enfermagem de reabilitação, a população poderá igualmente não o alcançar, o que poderá ter implicações na procura em cuidados.

Abstract Background: health quality is a multiprofessional task, in which rehabilitation nursing adds value, therefore understanding the social representation of rehabilitation nursing can provide relevant contributions to increase the visibility of the profession and promote changes in clinical practice practices and contexts. Objective: to describe the social representation of rehabilitation nursing for nurses. Methodology: qualitative, exploratory and descriptive study, in an accidental non-probabilistic sample with 110 participants, with nurses as the target population. The data collection was carried out through a test of free association of words, through electronic means, to the nurses in the network of contacts of a higher education institution. In data processing, we use the computer software IRAMUTEQ. Results: The central nucleus of the social representation evidenced the expressions autonomy, recovery and kinesitherapy, reinforced by the findings of the first periphery - independence, gait training and care. Emerging domains or common competencies, such as physical exercise and management, were less relevant to the structure of social representation. Conclusion: If it is not possible to build a social thought within the profession that translates the social mandate of rehabilitation nursing, the population may also not reach it, which could have implications for the demand for care.

https://doi.org/10.37914/riis.v4i1.124 11 downloads

13.

Lactobacillus pentosus ABHEAU-05: An in vitro digestión resistant lactic acid bacterium isolated from a traditional fermented Mexican beverage
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Ramírez, Meyli Claudia Escobar

; Ordaz, Judith Jaimez

; Iglesias, Valeria Abril Escorza

; Serrano, Gabriela Mariana Rodríguez

; López, Elizabeth Contreras

; Godínez, Juan Ramírez

; Ovando, Araceli Castañeda

; Estrada, Aurea Itzel Morales

; Reyes, Nancy Felix

; Olivares, Luis Guillermo González

Revista argentina de microbiología

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Dez 2020, Volume 52 Nº 4 Páginas 41 - 50

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The health benefits attributed to probiotics generate interest in the search of competent strains adapted to several ecological niches, especially those related to traditional beverages and foods of each country. Pineapple tepache, a traditional Mexican fermented beverage, was used for the isolation of lactic acid bacteria with probiotic potential, one of which withstood the in vitro tests. The isolated strain AB-05, which exhibited the tested probiotic functional properties, was designated as Lactobacillus pentosus ABHEAU-05. The sequence was registered in GenBank under access code MK587617. This study is the first report of a lactic acid bacterium with in vitro digestion resistance isolated from pineapple tepache. The survival of L. pentosus ABHEAU-05 in a symbiotic medium was proven using fermented milk enriched with inulin. The in vitro digestion-resistant probiotic activity of lactobacilli was measured through analysis of pH and proteolysis. Results showed that L. pentosus grew properly in fermented milk; therefore, this microorganism could be used in the manufacture of this kind of products. The concentration of L. pentosus reached up to 8.5 logCFU/ml after 40 h of fermentation. In addition, the production of peptides and the decrease in pH indicated the vigorous and active metabolic state of the lactic acid bacterium tested. The activity and the concentration of this microorganism were maintained during refrigeration. The results of this research conclude that L. plantarum ABHEAU-05 is an in vitro digestion-resistant microorganism that can be used as a starter culture for the production of functional foods of dairy origin.

Resumen Los beneficios a la salud atribuidos a los probióticos generan interés en la búsqueda de cepas competentes adaptadas a varios nichos ecológicos, especialmente los relacionados con bebidas y alimentos tradicionales de cada país. En este estudio, se aisló del tepache de pina, una bebida fermentada tradicional mexicana, una bacteria láctica resistente a la digestión in vitro. Entre 5 bacterias aisladas, una de ellas soportó las pruebas simuladas de digestión gastrointestinal. Se analizó la resistencia a sales biliares, a condiciones ácidas y al ataque enz-imático con pepsina. La bacteria aislada, que exhibió las propiedades funcionales probióticas referidas, fue identificada como Lactobacillus pentosus y designada como L. pentosus ABHEAU-05. La secuencia fue depositada en GenBank (acceso MK587617). Se comprobó la supervivencia de L. pentosus ABHEAU-05 en una leche fermentada adicionada con inulina y su resistencia a la digestión in vitro mediante el análisis del pH y la proteólisis. Los resultados muestran que la leche fermentada es una matriz adecuada, donde L. pentosus ABHEAU-05 se desarrolla sin inconvenientes, alcanzando un título de 8,5 logufc/ml después de 40 h de fermentación. Además, la producción de péptidos y el descenso del pH indicaron el estado metabólico vigoroso y activo del microorganismo probiótico. Se concluye que L. pentosus ABHEAU-05 es un microorganismo resistente a la digestión in vitro, que puede servir como cultivo iniciador para la producción de alimentos de origen lácteo. Este es el primer informe acerca del aislamiento de una bacteria ácido láctica resistente a la digestión in vitro a partir del tepache de piña.

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14.

COVID-19: Temas de interés para el cirujano
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Arbeláez-Salgado, María Adelaida

; Cadavid-Congote, Andrés

; Flórez-Filomeno, Daniela Rosa

; Garcés-Otero, Juan Sebastián

; Gómez-Machado, Agustín

; Guzmán-Arango, Carolina

; Londoño-Restrepo, Daniella

; Maya-López, Carolina

; Mejía-Cardona, Paula Andrea

; Molina-Rodríguez, María Alejandra

; Molina-Velásquez, Juan Santiago

; Ochoa-Pineda, Alejandra

; Paredes-Minotas, Laura

; Ramírez-Ceballos, Mariana

; Restrepo-Gómez, Camilo

; Sanín-Osorio, María Alejandra

; Serrano-De Castro, Javier Andrés

; Turizo-Mejía, Juan José

; Uribe-Valencia, Andrés

; Velásquez-Hoyos, Andrés

; Sierra-Sierra, Sebastián

Revista Colombiana de Cirugía

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Jun 2020, Volume 35 Nº 2 Páginas 153 - 161

Resumo: Es | Texto: Es | PDF: Es

https://doi.org/10.30944/20117582.612 874 downloads

15.

Asociación entre Artritis Reumatoidea y otras enfermedades autoinmunes
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Serrano, Eliana Rebeca

; Pérez, Silvana Karina

; Bande, Juan Manuel

; Sosa, Julia

; Kohan, María Paula

; Santa Cruz, María Julia

; Medina, María Alejandra

; Klajn, Diana Silvia

; Ángel, José

; Benegas, Mariana

; Saturanski, Etel

; Quintana, Rosana

; Pons-Estel, Bernardo

; Pereira, Dora

; Dellepiane, Analía

; Correa, María de los Ángeles

; Citera, Gustavo

; Sacnum, Mónica

; Hartvig, Claudia

; Demarchi, Julia

; Bartel, Guillermo

; Gómez, Andrea

; Kirmayr, Karin

; Velasco Zamora, José Luis

; Chichotky, Yamila

; Salazar, María Marta

; Rillo, Oscar

; Bohr, Analía

; Pérez Dávila, Adriana

; Najera, Hugo

; Chuquimia, Jearmany René

; Secco, Anastasia

; Martínez, Alejandro

; Buschiazzo, Emilio

; Juárez, Vicente

; Raiti, Laura

; Cruzat, Vanesa

; Smichowski, Andrea

; Casado, Gustavo

; Zelaya, David

; Álvarez, Damaris

; Kerzberg, Eduardo Mario

; Rosa, Javier

; García, María Victoria

; Retamozo, Cinthya

; Costi, Ana Carolina

; Pena, Claudia

; Maldonado Ficco, Hernán

; Papasidero, Silvia Beatriz

Revista argentina de reumatología

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Jun 2020, Volume 31 Nº 2 Páginas 18 - 23

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Objectives: To determine the frequency of autoimmune diseases (AID) in Rheumatoid Arthritis (RA) patients and to compare this frequency between patients with and without RA or other rheumatologic AID. Methods: Multicenter, observational, analytical, retrospective study. Consecutive patients with diagnosis of RA (ACR/EULAR 2010) were included. Patients with initial diagnosis of primary ostearthritis (OA) were used as control group. Results: A total of 1549 patients were included: 831 RA (84% women, mean age 55.2 [±13.6]) and 718 OA (82% women, mean age 67 [± 11.1]). The frequency of AID in the RA group was 22% (n=183). RA patients showed higher frequency of rheumatologic AID (9.4 vs 3.3%, p< 0.001), and lower frequency of non-rheumatologic AID than OA patients (15.3 vs 20.5%, p= 0.007). The most prevalent rheumatic AID was Sjögren’s Syndrome, which was more frequent in the AR group (87.2 vs 29.2%, p<0.001). The frequency of rheumatologic AID in RA patients was higher in those with erosive RA (11 vs 6.8%, p=0.048). Conclusion: The frequency of AID in RA patients was 22%. Rheumatologic AID were more frequent in RA patients, whereas non-rheumatologic AID prevailed in OA patients.

Objetivos: Determinar la frecuencia de enfermedades autoinmunes (EAI) en pacientes con Artritis Reumatoidea (AR) y comparar la frecuencia de EAI entre pacientes con AR y sin AR ni otra EAI reumatológica. Material y Métodos: Estudio multicéntrico, observacional, analítico, retrospectivo. Se incluyeron pacientes consecutivos con AR (ACR/EULAR 2010) y como grupo control pacientes con diagnóstico inicial de Osteoartritis primaria (OA). Resultados: Se incluyeron 1549 pacientes: 831 con AR (84% mujeres, edad media 55.2 años [DE 13.6]) y 718 con OA (82% mujeres, edad media 67 años [DE 11.1]). La frecuencia de EAI en el grupo AR fue del 22% (n=183). Estos presentaron mayor frecuencia de EAI reumatológicas (9.4 vs 3.3%, p< 0.001), y menor frecuencia de EAI no reumatológicas que aquellos con OA (15.3 vs 20.5, p=0.007). La EAI reumatológica más prevalente fue el Síndrome de Sjögren, el cual fue más frecuente en el grupo AR (87.2 vs 29.2%, p< 0,001). La frecuencia de EAI reumatológicas en los pacientes con AR fue mayor en la forma erosiva (11 vs 6.8%, p=0.048). Conclusión: La frecuencia de EAI en los pacientes con AR fue del 22%, en quienes predominaron las de etiología reumatológica mientras que, las no reumatológicas predominaron en pacientes con OA.

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